4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60756 | NLRP3 antagonist 1 | ||
NLRP3 antagonist 1 shows potential for the cancer research that is a potent NLRP3 antagonist. NLRP3 is involved in the body's intrinsic immunity against stress injury and pathogenic infections that is mainly expressed in... | |||
T26432 | A68930 | A 68930,A70108,A-68930,A 70108,A-70108 | |
A 68930 is a dopamine D-1 receptor antagonist. A 68930 inhibits NLRP3 inflammasome activity. | |||
T81579 | P2X7 receptor antagonist-4 | ||
Compound 14a (P2X7 receptor antagonist-4) is a P2X7R antagonist with IC50 values of 64.7 nM in humans and 10.1 nM in mice. It inhibits the activation of the NLRP3 inflammasome, which subsequently reduces the expression o... | |||
T71651 | GSK1370319A | ||
GSK1370319A is a potent P2X7 antagonist (IC50 = 3.2 nM). GSK1370319A inhibits ATP-induced increase in IL-1β release and caspase 1 activation in lipopolysaccharide (LPS)-primed mixed glia by blocking assembly of the infla... |